Early neurotransmitter phenotype specification in Xenopus laevis
نویسندگان
چکیده
منابع مشابه
The role of voltage-gated calcium channels in neurotransmitter phenotype specification: Coexpression and functional analysis in Xenopus laevis
Calcium activity has been implicated in many neurodevelopmental events, including the specification of neurotransmitter phenotypes. Higher levels of calcium activity lead to an increased number of inhibitory neural phenotypes, whereas lower levels of calcium activity lead to excitatory neural phenotypes. Voltage-gated calcium channels (VGCCs) allow for rapid calcium entry and are expressed duri...
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This investigation has used histological techniques and the scanning electron microscope to establish the presence of an apical ectodermal ridge in the developing limbs of Xenopus laevis. The ridge appeared at stage 50, reached its maximal size at stage 51, and subsequently disappeared by stage 53. The course of the ridge was consistently related to a marginal sinus in the underlying mesenchyme...
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We have further analysed the roles of mesoderm induction and dorsalization in the formation of a regionally specified mesoderm in early embryos of Xenopus laevis. First, we have examined the regional specificity of mesoderm induction by isolating single blastomeres from the vegetalmost tier of the 32-cell embryo and combining each with a lineage-labelled (FDA) animal blastomere tier. Whereas do...
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Xenopus laevis provides a number of advantages to studies on cardiovascular development. The embryos are fairly large, are easy to obtain, and can develop at ambient temperature in simple buffer solutions. Although classic descriptions of heart development exist, the ability to use whole-mount immunohistochemical methods and confocal microscopy may enhance the ability to understand both normal ...
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Eggs of Xenopus laevis contain exceptionally large amounts of materials involved in chromosome replication. This maternal stockpile allows an embryo to produce about 80 000 cells in less than 24 h. The adaptations which achieve this involve the mechanisms of both DNA replication and chromatin assembly.
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2008
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2008.05.408